Plasma: Multi Screen
Ah, working with more than one screen, nice and convenient, but always has been the scourge of usability, due to broken hardware and software, on every platform you can imagine. And yes, on Plasma we are notorious to have several problems with regard to multi screens, which spurred many bug reports.
For Plasma 5.27 we did a big refactor on how the screens are managed (and how they are mapped to desktops and panels) which hopefully should solve many of those issues, creating a much more predictable experience, both for “fixed” multi screen setups (like a setup at your desk) and “on the go” (like attaching a projector at a conference).